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1

Comparison of clot lysis activity and biochemical properties of originator tenecteplase (Metalyse®) with those of an alleged biosimilar

Kliche, Werner, Krech, Ingo, Michel, Martin C., Sangole, Nishant V., Sathaye, Sadhana

Journal:

Frontiers in Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.14 MB

english, 2014

2

ChemInform Abstract: Biologically Active Metabolites from Fungi. Part 8. Dihydroisocoumarins from Fungi: Isolation, Structure Elucidation, Circular Dichroism and Biological Activity.

K. KROHN, R. BAHRAMSARI, U. FLOERKE, K. LUDEWIG, C. KLICHE-SPORY, A. MICHEL, H.-J. AUST, S. DRAEGER, B. SCHULZ, S. ANTUS

Journal:

Year:

1997

File:

PDF, 29 KB

1997

3

ChemInform Abstract: Synthesis and in vitro Evaluation of Novel Highly Potent Coumarin Inhibitors of Gyrase B.

Patrick Laurin, Didier Ferroud, Michel Klich, Claudine Dupuis-Hamelin, Pascale Mauvais, Patrice Lassaigne, Alain Bonnefoy, Branislav Musicki

Journal:

Year:

1999

File:

PDF, 36 KB

1999

4

ChemInform Abstract: A Facile Route to Aryl Amines: Nucleophilic Substitution of Aryl Triflates.

Laurent Schio, Guy Lemoine, Michel Klich

Journal:

Year:

2000

File:

PDF, 32 KB

2000

5

ChemInform Abstract: Synthesis and Biological Evaluation of Coumarincarboxylic Acids as Inhibitors of Gyrase B. L-Rhamnose as an Effective Substitute for L-Noviose.

Didier Ferroud, Jeannine Collard, Michel Klich, Claudine Dupuis-Hamelin, Pascale Mauvais, Patrice Lassaigne, Alain Bonnefoy, Branislav Musicki

Journal:

Year:

2000

File:

PDF, 27 KB

2000

6

ChemInform Abstract: Stereoselective Synthesis of 5-Monoalkyl and 5,5-Dialkylsubstituted Noviose Derivatives.

Anne-Marie Periers, Patrick Laurin, Yannick Benedetti, Sylvette Lachaud, Didier Ferroud, Alain Iltis, Jean-Luc Haesslein, Michel Klich, Guillaume L'Hermite, Branislav Musicki

Journal:

Year:

2000

File:

PDF, 28 KB

2000

7

ChemInform Abstract: Coumarin Inhibitors of Gyrase B with N-Propargyloxy-carbamate as an Effective Pyrrole Bioisostere.

Anne-Marie Periers, Patrick Laurin, Didier Ferroud, Jean-Luc Haesslein, Michel Klich, Claudine Dupuis-Hamelin, Pascale Mauvais, Patrice Lassaigne, Alain Bonnefoy, Branislav Musicki

Journal:

Year:

2000

File:

PDF, 32 KB

2000

8

ChemInform Abstract: Synthesis of Isothiochroman 2,2-Dioxide and 1,2-Benzooxathiin 2,2-Dioxide Gyrase B Inhibitors.

Christophe Peixoto, Patrick Laurin, Michel Klich, Claudine Dupuis-Hamelin, Pascale Mauvais, Patrice Lassaigne, Alain Bonnefoy, Branislav Musicki

Journal:

Year:

2000

File:

PDF, 33 KB

2000

9

ChemInform Abstract: Tosylates in Palladium-Catalyzed Coupling Reactions. Application to the Synthesis of Arylcoumarin Inhibitors of Gyrase B.

Laurent Schio, Fabienne Chatreaux, Michel Klich

Journal:

Year:

2000

File:

PDF, 31 KB

2000

10

ChemInform Abstract: Fine Tuning of Physico-Chemical Parameters to Optimize a New Series of Novobiocin Analogues.

Laurent Schio, Fabienne Chatreaux, Veronique Loyau, Michel Murer, Anne Ferreira, Pascale Mauvais, Alain Bonnefoy, Michel Klich

Journal:

Year:

2001

File:

PDF, 30 KB

2001

11

Noviose mimics of the coumarin inhibitors of gyrase B

Branislav Musicki, Anne-Marie Periers, Laurent Piombo, Patrick Laurin, Michel Klich, Claudine Dupuis-Hamelin, Patrice Lassaigne, Alain Bonnefoy

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 226 KB

english, 2003

12

Dihydroisocoumarins from fungi: Isolation, structure elucidation, circular dichroism and biological activity

Karsten Krohn, Rahim Bahramsari, Ulrich Flörke, Kerstin Ludewig, Christine Kliche-Spory, Andreas Michel, Hans-Jürgen Aust, Siegfried Draeger, Barbara Schulz, Sándor Antus

Journal:

Year:

1997

Language:

english

File:

PDF, 667 KB

english, 1997

13

Synthese de n-(tetrazol-5-yl) azetidin-2-ones

Michel Klich, Georges Teutsch

Journal:

Year:

1986

Language:

english

File:

PDF, 463 KB

english, 1986

14

Synthesis of isothiochroman 2,2-dioxide and 1,2-benzooxathiin 2,2-dioxide gyrase B inhibitors

Christophe Peixoto, Patrick Laurin, Michel Klich, Claudine Dupuis-Hamelin, Pascale Mauvais, Patrice Lassaigne, Alain Bonnefoy, Branislav Musicki

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 168 KB

english, 2000

15

Synthese de N-(tetrazol-5-yl) azetidin-2-ones

Michel Klich, Georges Teutsch

Journal:

Tetrahedron Letters

Year:

1984

File:

PDF, 203 KB

1984

16

Stereoselective synthesis of 5-monoalkyl and 5,5-dialkylsubstituted noviose derivatives

Anne-Marie Periers, Patrick Laurin, Yannick Benedetti, Sylvette Lachaud, Didier Ferroud, Alain Iltis, Jean-Luc Haesslein, Michel Klich, Guillaume L’Hermite, Branislav Musicki

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 183 KB

english, 2000

17

Tosylates in palladium-catalysed coupling reactions. Application to the synthesis of arylcoumarin inhibitors of gyrase B

Laurent Schio, Fabienne Chatreaux, Michel Klich

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 212 KB

english, 2000

18

Fine Tuning of physico-chemical parameters to optimise a new series of novobiocin analogues

Laurent Schio, Fabienne Chatreaux, Véronique Loyau, Michel Murer, Anne Ferreira, Pascale Mauvais, Alain Bonnefoy, Michel Klich

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 147 KB

english, 2001

19

Synthesis of an N-(tetrazol-5-yl) azetidin-2-one from L-tartaric acid

Michel Klich, Georges Teutsch

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 117 KB

english, 1993

20

Synthesis and in vitro evaluation of novel highly potent coumarin inhibitors of gyrase B

Patrick Laurin, Didier Ferroud, Michel Klich, Claudine Dupuis-Hamelin, Pascale Mauvais, Patrice Lassaigne, Alain Bonnefoy, Branislav Musicki

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 367 KB

english, 1999

21

Synthesis and biological evaluation of coumarincarboxylic acids as inhibitors of gyrase B. L-rhamnose as an effective substitute for L-noviose

Didier Ferroud, Jeannine Collard, Michel Klich, Claudine Dupuis-Hamelin, Pascale Mauvais, Patrice Lassaigne, Alain Bonnefoy, Branislav Musicki

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 354 KB

english, 1999

22

Coumarin inhibitors of gyrase B with N-propargyloxy-carbamate as an effective pyrrole bioisostere

Anne-Marie Periers, Patrick Laurin, Didier Ferroud, Jean-Luc Haesslein, Michel Klich, Claudine Dupuis-Hamelin, Pascale Mauvais, Patrice Lassaigne, Alain Bonnefoy, Branislav Musicki

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 183 KB

english, 2000

23

DNA Gyrase Interaction with Coumarin-Based Inhibitors: The Role of the Hydroxybenzoate Isopentenyl Moiety and the 5‘-Methyl Group of the Noviose†

Lafitte, Daniel, Lamour, Valérie, Tsvetkov, Philippe O., Makarov, Alexander A., Klich, Michel, Deprez, Pierre, Moras, Dino, Briand, Claudette, Gilli, Robert

Journal:

Year:

2002

Language:

english

File:

PDF, 233 KB

english, 2002

24

Synthesis of a fluorescent steroid derivative with high affinities for the glucocorticoid and progesterone receptors

Georges Teutsch, Michel Klich, Françoise Bouchoux, Evelyne Cerede, Daniel Philibert

Journal:

Year:

1994

Language:

english

File:

PDF, 544 KB

english, 1994

25

Reduced functionality in everyday activities of patients with self-reported heart failure hospitalization — Population-based study results

Skalska, Anna, Wizner, Barbara, Więcek, Andrzej, Zdrojewski, Tomasz, Chudek, Jerzy, Klich-Rączka, Alicja, Piotrowicz, Karolina, Błędowski, Piotr, Mossakowska, Małgorzata, Michel, Jean-Pierre, Grodzick

Journal:

International Journal of Cardiology

Year:

2014

Language:

english

File:

PDF, 304 KB

english, 2014

26

A Facile Route to Aryl Amines: Nucleophilic Substitution of Aryl Triflates

Schio, Laurent, Lemoine, Guy, Klich, Michel

Journal:

Year:

1999

Language:

english

File:

PDF, 63 KB

english, 1999

27

Status and population structure of a hunted population of Marco Polo Argali Ovis ammon polii (Cetartiodactyla, Bovidae) in Southeastern Tajikistan

Valdez, Raul, Michel, Stefan, Subbotin, Andrey, Klich, Daniel

Journal:

Year:

2016

Language:

english

File:

PDF, 567 KB

english, 2016

28

Use of Feedback in Reducing Television Watching

Jason, Leonard A., Klich, Michele M.

Journal:

Psychological Reports

Year:

1982

Language:

english

File:

PDF, 117 KB

english, 1982

29

Clustering of geriatric deficits emerges to be an essential feature of ageing - results of a cross-sectional study in Poland

Piotrowicz, Karolina, Pac, Agnieszka, Skalska, Anna Barbara, Chudek, Jerzy, Klich-Rączka, Alicja, Szybalska, Aleksandra, Michel, Jean-Pierre, Grodzicki, Tomasz

Journal:

Year:

2016

Language:

english

File:

PDF, 458 KB

english, 2016

30

Modified Blalock-Taussig shunt in newborn infants

Ilbawi, Michel N., Grieco, John, DeLeon, Serafin Y., Idriss, Farouk S., Muster, Alexander J., Berry, Teresa E., Klich, Janice

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

1984

File:

PDF, 2.26 MB

1984